Table 3 Correlates of suboptimal adherence: Univariate and multivariate logistic regression
Factor | Adherent (n鈥�=鈥�439) n (%) | Suboptimally adherent (n鈥�=鈥�62) n (%) | OR (95% CI) | p | AOR (95% CI) | p |
|---|---|---|---|---|---|---|
Age: < 25 years* | 27 (6.2) | 23 (22.6) | 4.45 (2.19鈥�9.07) | &濒迟;鈥�0.001 | 4.83 (2.28鈥�10.22) | &濒迟;鈥�0.001 |
On PrEP鈥�<鈥�12 months | 220 (50.1) | 33 (53.2) | 1.13 (0.67鈥�1.93) | 0.647 | 听 | 听 |
Months of available chart data [M(SD)] | 8.88 (3.47) | 8.83 (3.35) | 1.00 (0.92鈥�1.08) | 0.901 | 听 | 听 |
PrEP regimen type鈥�=鈥塶on-daily* | 23 (5.2) | 8 (12.9) | 2.68 (1.14鈥�6.29) | 0.024 | 2.94 (1.19鈥�7.22) | 0.019 |
Missed any PrEP appointments* | 102 (23.2) | 23 (37.1) | 1.95 (1.11鈥�3.41) | 0.020 | 1.97 (1.09鈥�3.55) | 0.025 |
Hazardous alcohol use* | 35 (8.0) | 9 (14.5) | 1.96 (0.89鈥�4.30) | 0.094 | 1.71 (0.72鈥�4.02) | 0.223 |
Substance use (any) | 136 (31.0) | 29 (46.8) | 1.96 (1.14鈥�3.35) | 0.014 | 听 | 听 |
Use of specific substances: | 听 | 听 | 听 | 听 | 听 | 听 |
Cannabis | 46 (10.5) | 9 (14.5) | 1.45 (0.67鈥�3.13) | 0.343 | 听 | 听 |
Cocaine | 29 (6.6) | 6 (9.7) | 1.52 (0.60鈥�3.81) | 0.378 | 听 | 听 |
Poppers* | 21 (4.8) | 9 (14.5) | 3.38 (1.47鈥�7.76) | 0.004 | 2.41 (0.97鈥�5.98) | 0.058 |
Club Drugs* | 89 (20.3) | 22 (35.5) | 2.16 (1.22鈥�3.82) | 0.008 | 1.97 (1.01鈥�3.68) | 0.033 |
Use of specific club drugs: | 听 | 听 | 听 | 听 | 听 | 听 |
Methamphetamine | 78 (16.6) | 11 (25.8) | 1.74 (0.94鈥�3.25) | 0.080 | 听 | 听 |
MDMA/Ecstasy | 19 (4.3) | 6 (9.7) | 2.37 (0.91鈥�6.18) | 0.078 | 听 | 听 |
GHB | 6 (1.4) | 5 (8.1) | 6.33 (1.87鈥�21.41) | 0.003 | 听 | 听 |
Hallucinogens | 1 (0.2) | 1 (1.6) | 7.18 (0.44-116.28) | 0.165 | 听 | 听 |
Mental health issue (any)* | 109 (24.8) | 22 (35.5) | 1.67 (0.95鈥�2.93) | 0.076 | 1.62 (0.88鈥�2.97) | 0.119 |
Specific mental health issues: | 听 | 听 | 听 | 听 | 听 | 听 |
Depression | 58 (13.2) | 12 (19.4) | 1.72 (0.94鈥�3.17) | 0.080 | 听 | 听 |
Anxiety disorder | 53 (12.1) | 12 (19.4) | 1.69 (0.91鈥�3.14) | 0.098 | 听 | 听 |
Bipolar disorder | 3 (0.7) | 2 (3.2) | 4.84 (0.79鈥�29.59) | 0.087 | 听 | 听 |
Borderline personality disorder (BPD) | 1 (0.2) | 0 (0.0) | -- | -- | 听 | 听 |
Obsessive compulsive disorder (OCD) | 3 (0.7) | 1 (1.6) | 2.38 (0.24鈥�23.27) | 0.455 | 听 | 听 |
Post-traumatic stress disorder (PTSD) | 7 (1.6) | 0 (0.0) | -- | -- | 听 | 听 |
Sexual behavior indicators | 听 | 听 | 听 | 听 | 听 | 听 |
Condomless anal sex | 294 (67.0) | 45 (72.6) | 1.31 (0.72鈥�2.36) | 0.378 | 听 | 听 |
Sexually transmitted infection (STI) | 170 (38.7) | 23 (37.1) | 0.93 (0.54鈥�1.62) | 0.805 | 听 | 听 |