Table 2 Correlates of any nonadherence: Univariate and multivariate logistic regression
Factor | Adherent (n鈥�=鈥�313) n (%) | Nonadherent (n鈥�=鈥�188) n (%) | OR (95% CI) | p | AOR (95% CI) | p |
|---|---|---|---|---|---|---|
Age: < 25 years* | 15 (4.8) | 26 (13.8) | 3.19 (1.64鈥�6.19) | &濒迟;鈥�0.001 | 3.08 (1.54鈥�6.15) | &濒迟;鈥�0.001 |
On PrEP鈥�<鈥�12 months* | 143 (45.7) | 110 (58.5) | 1.68 (1.16鈥�2.42) | 0.006 | 1.42 (0.70鈥�2.90) | 0.331 |
Months of available chart data [Mean(SD)]* | 9.22 (3.42) | 8.31 (3.44) | 0.93 (0.88鈥�0.98) | 0.004 | 1.05 (0.94鈥�1.17) | 0.401 |
PrEP regimen type鈥�=鈥塶on-daily | 19 (6.1) | 12 (6.4) | 1.06 (0.50鈥�2.23) | 0.888 | 听 | 听 |
Missed any PrEP appointments | 84 (26.8) | 41 (21.8) | 0.76 (0.50鈥�1.17) | 0.209 | 听 | 听 |
Hazardous alcohol use | 24 (7.7) | 20 (10.6) | 1.43 (0.77鈥�2.67) | 0.257 | 听 | 听 |
Substance use (any) | 82 (26.2) | 83 (44.1) | 2.23 (1.52鈥�3.27) | &濒迟;鈥�0.001 | 听 | 听 |
Use of specific substances: | 听 | 听 | 听 | 听 | 听 | 听 |
Cannabis | 31 (9.9) | 24 (12.8) | 1.33 (0.76鈥�2.35) | 0.322 | 听 | 听 |
Cocaine* | 17 (5.4) | 18 (9.6) | 1.84 (0.93鈥�3.67) | 0.082 | 1.24 (0.58鈥�2.64) | 0.577 |
Poppers | 17 (5.4) | 13 (6.9) | 1.29 (0.61鈥�2.73) | 0.499 | 听 | 听 |
Club Drugs* | 47 (15.0) | 64 (34.0) | 2.92 (1.90鈥�4.50) | &濒迟;鈥�0.001 | 2.71 (1.65鈥�4.47) | &濒迟;鈥�0.001 |
Use of specific club drugs: | 听 | 听 | 听 | 听 | 听 | 听 |
Methamphetamine | 39 (12.5) | 50 (26.6) | 2.55 (1.60鈥�4.06) | &濒迟;鈥�0.001 | 听 | 听 |
MDMA/Ecstasy | 12 (3.8) | 13 (6.9) | 1.86 (0.83鈥�4.17) | 0.130 | 听 | 听 |
GHB | 3 (1.0) | 8 (4.3) | 4.59 (1.20-17.53) | 0.026 | 听 | 听 |
Hallucinogens | 1 (0.3) | 1 (0.5) | 1.67 (0.10-26.83) | 0.718 | 听 | 听 |
Mental health issue (any)* | 91 (29.1) | 40 (21.3) | 0.66 (0.43鈥�1.01) | 0.055 | 0.68 (0.43鈥�1.07) | 0.096 |
Specific mental health issues: | 听 | 听 | 听 | 听 | 听 | 听 |
Depression | 66 (21.0) | 30 (16.0) | 0.71 (0.44鈥�1.14) | 0.159 | 听 | 听 |
Anxiety disorder | 63 (20.1) | 28 (14.9) | 0.69 (0.43鈥�1.13) | 0.143 | 听 | 听 |
Bipolar disorder | 2 (0.6) | 2 (1.1) | 2.52 (0.42鈥�15.23) | 0.313 | 听 | 听 |
Borderline personality disorder (BPD) | 1 (0.3) | 0 (0.0) | 1.00 (0.00鈥�0.00) | 1.000 | 听 | 听 |
Obsessive compulsive disorder (OCD) | 3 (1.0) | 1 (0.5) | 0.55 (0.06鈥�5.35) | 0.609 | 听 | 听 |
Post-traumatic stress disorder (PTSD) | 6 (1.9) | 1 (0.2) | 0.27 (0.33鈥�2.29) | 0.232 | 听 | 听 |
Sexual behavior indicators | 听 | 听 | 听 | 听 | 听 | 听 |
Condomless anal sex* | 193 (61.7) | 146 (77.7) | 2.16 (1.43鈥�3.26) | &濒迟;鈥�0.001 | 1.83 (1.19鈥�2.83) | 0.006 |
Sexually transmitted infection (STI) | 117 (37.4) | 76 (40.4) | 1.14 (0.79鈥�1.65) | 0.498 | 听 | 听 |