Intervention arm | Control arm | |
---|---|---|
PROMISE-EPI prevention package | Zambian standard of care | |
- POC for maternal viral load monitoring at EPI-2 and M6 - Immediate single-drug (lamivudine) infant prophylaxis initiation in case of mother viral load ≥ 1000cp/ml - Monthly visits for infants on lamivudine | Before 2020: - Viral load monitoring every 6 months during the breastfeeding period | After 2020: - Extended three drug infant prophylaxis (AZT/3TC + NVP) in case of maternal viral load ≥ 1000 cp/ml at 10 weeks and maternal viral load follow-up every 3 months |