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Table 5 Hazard ratios and 95% confidence intervals of incident PCa related to MetS and sociodemographic factors

From: Machine learning algorithms that predict the risk of prostate cancer based on metabolic syndrome and sociodemographic characteristics: a prospective cohort study

Variables

Univariate Analysis

Multivariate Analysis

Ìý

HR (95% CI)

P value

HR (95% CI)

P value

Age

1.13 (1.11–1.15)

&±ô³Ù; 0.001

1.14 (1.12–1.16)

&±ô³Ù; 0.001

Educational level

ÌýÌýÌýÌý

High school graduate or less

1.00

0.453

1.00

0.612

College or higher

0.90 (0.68–1.19)

Ìý

1.08 (0.80–1.46)

Ìý

First-degree family history of prostate cancer

No

1.00

Ìý

1.00

Ìý

Yes

3.73 (1.84–7.57)

&±ô³Ù; 0.001

4.00 (1.97–8.14)

&±ô³Ù; 0.001

Alcohol consumption

ÌýÌýÌýÌý

Nondrinkers

1.00

Ìý

1.00

Ìý

Ex-drinkers

1.18 (0.73–1.89)

0.504

1.91 (1.18–3.10)

0.009

Current drinkers

2.16 (1.14–4.07)

0.018

1.85 (0.98–3.51)

0.060

Smoking status

ÌýÌýÌýÌý

Nonsmokers

1.00

Ìý

1.00

Ìý

Ex-smokers

0.51 (0.35–0.73)

&±ô³Ù; 0.001

0.86 (0.59–1.26)

0.445

Current smokers

0.94 (0.68–1.32)

0.736

0.87 (0.62–1.22)

0.418

Household income (10,000 won/month)

<200

1.00

Ìý

1.00

Ìý

200–400

0.95 (0.61–1.48)

0.821

1.74 (1.11–2.74)

0.016

>400

0.81 (0.53–1.23)

0.320

1.82 (1.15–2.88)

0.011

Marital status

ÌýÌýÌýÌý

Married or cohabitating

1.00

0.173

1.00

0.990

Others

0.59 (0.28–1.26)

Ìý

1.00 (0.47–2.12)

Ìý

Regular exercise

ÌýÌýÌýÌý

No

1.00

0.344

1.00

0.331

Yes

1.15 (0.86–1.53)

Ìý

0.86 (0.64–1.16)

Ìý

Metabolic syndrome

ÌýÌýÌýÌý

No

1.00

0.192

1.00

0.860

Yes

1.23 (0.90–1.67)

Ìý

0.95 (0.56–1.61)

Ìý

Waist circumference

ÌýÌýÌýÌý

Men < 90Ìýcm

1.00

0.594

1.00

0.332

Men ≥ 90Ìýcm

1.08 (0.82–1.42)

Ìý

1.17 (0.85–1.60)

Ìý

HDL

ÌýÌýÌýÌý

Men ≥ 40Ìýmg/dL

1.00

0.892

1.00

0.448

Men < 40Ìýmg/dL

1.03 (0.71–1.48)

Ìý

1.18 (0.78–1.78)

Ìý

Triglycerides

ÌýÌýÌýÌý

<150Ìýmg/dL

1.00

0.230

1.00

0.800

≥150Ìýmg/dL

0.83 (0.62–1.12)

Ìý

0.96 (0.67–1.37)

Ìý

Blood pressure

ÌýÌýÌýÌý

<130/85 mmHg

1.00

0.032

1.00

0.633

≥130/85 mmHg

1.35 (1.03–1.77)

Ìý

1.08 (0.79–1.47)

Ìý

Fasting glucose

ÌýÌýÌýÌý

<100Ìýmg/dL or no history of diabetes

1.00

&±ô³Ù; 0.001

1.00

0.370

≥100Ìýmg/dL or history of diabetes

1.77 (1.33–2.36)

Ìý

1.17 (0.83–1.63)

Ìý
  1. HR: hazard ratio; CI: confidence interval