The progress of mother-to-child transmission of Human Immunodeficiency Virus (HIV) after Dolutegravir (DTG) optimization program: evidence from a multicenter cohort study in Ethiopia

Table 4 Multivariate logistic regression analysis of MTCT outcomes by ART regimen, adjusted for age, study site, hospital level, place of delivery, and WHO staging

Baseline difference Variables	Category	Perinatal MTCT			Final MTCT			Breastfeeding MTCT
Baseline difference Variables	Category	AOR	95% CI for AOR		AOR	95%CI for AOR		AOR	95% CI for AOR
ART regimen	罢顿贵鈥�+鈥�3罢颁鈥�+鈥塃贵痴	Ref(1)	听	听	Ref(1)	听	听	Ref(1)	听	听
ART regimen	罢顿贵鈥�+鈥�3罢颁鈥�+鈥塂罢骋	0.23	0.09	0.82	0.23	0.06	0.85	0.18	0.02	1.96
Age	15鈥�24	Ref (1)	听	听	Ref(1)	听	听	Ref(1)	听	听
	25鈥�29	0.83	0.28	2.41	0.88	0.24	3.26	0.79	0.13	4.86
	30鈥�34	0.87	0.26	2.85	1.16	0.29	4.66	0.36	0.03	4.33
	>=35	1.18	0.31	4.45	1.58	0.33	7.59	0.62	0.05	7.38
Study site	Addis Ababa	Ref(1)	听	听	Ref(1)	听	听	Ref(1)	听	听
	Oromia	5.77	1.22	27.41	听	0.00	.	1.63	0.21	12.59
	SNNPR	6.38	0.99	41.23	0.00	0.00	.	0.59	0.03	10.73
	Sidama	11.94	2.23	63.90	0.00	0.00	.	2.69	0.20	37.03
Level of hospital	Primary	Ref(1)	听	听	Ref(1)	听	听	Ref(1)	听	听
	General	0.71	0.19	2.70	0.67	0.13	3.41	1.19	0.11	13.33
	Tertiary	0.75	0.26	2.19	1.24	0.34	4.50	0.63	0.08	5.31
Place of delivery	Study site hospital	Ref(1)	听	听	Ref(1)	听	听	Ref(1)	听	听
	Other healthcare facility	2.899	1.015	8.283	3.385	1.039	11.030	2.004	0.23	17.61
	Home delivery	6.83	0.75	2.28	10.02	0.99	101.78	0.00	0.00	.
WHO staging	1	Ref(1)	听	听	Ref(1)	听	听	Ref(1)	听	听
	2	4.82	0.93	25.03	2.45	0.24	25.27	7.26	0.68	78.07
	3	0.00	0.00	.	0.00	0.00	.	0.00	0.00	.
	4	0.00	0.00	.	0.00	0.00	.	0.00	0.00	.

Table听4 presents the results of the multivariate logistic regression analysis for MTCT outcomes by ART regimen, adjusted for age, study site, hospital level, place of delivery, and WHO staging. COR represents the crude odds ratio, while AOR denotes the adjusted odds ratio. Significant values, indicated in bold, have a P-value of less than 0.05.

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