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Table 3 Baseline demographics, pregnancy history, and HIV-Related characteristics of study participants using DTG- or EFV-only containing ART regimens for PMTCT Care (2017鈥2022) in selected hospitals in Ethiopia (N鈥=鈥2053)

From: The progress of mother-to-child transmission of Human Immunodeficiency Virus (HIV) after Dolutegravir (DTG) optimization program: evidence from a multicenter cohort study in Ethiopia

Baseline characteristics

Category

罢顿贵鈥+鈥3罢颁鈥+鈥塃贵痴

罢顿贵鈥+鈥3罢颁鈥+鈥塂罢骋

Total

P-value

Birth cohort year

2017

63(5.1)

0(0)

63(3.1)

0.000

2018

388(31.5)

0(0)

388(18.9)

2019

484(39.3)

0(0)

484(23.6)

2020

263(21.4)

89(10.8)

352(17.1)

2021

22(1.8)

392(47.6)

414(20.2)

2022

10(0.8)

342(41.6))

352(17.1)

Age

Age in category

Median (IQR)

28(25,32)

29(25,34)

28(25,33)

0.000

15鈥24

159(19.3)

127(21.9)

286(20.4)

25鈥29

304(36.8)

179(30.9)

483(34.4)

30鈥34

245(29.7)

140(24.2)

385(27.4)

>=35

117(14.2)

133(23.0)

250(17.8)

Study hospital region

Addis Ababa

408(33.2)

227(27.6)

635(30.9)

0.000

Oromia

401(32.6)

288(35.0)

689(33.6)

SNNPR

330(26.8)

273(33.2)

603(29.4)

Sidama

91(7.4)

35(4.3)

126(6.1)

Hospital levels

Primary

92(7.5)

78(9.5)

170(8.3)

0.000

General 1

139(11.3)

194( 23.6)

333(16.2)

Tertiary

999(81.2)

551(67.0)

1550(76.5)

Partner HIV status

Positive

959(78.0)

649(78.9)

1606(78.3)

0.532

Negative

119(9.7)

85(10.3)

204(9.9)

Unknown

152(12.4)

89(10.8)

241(11.7)

WHO staging

1

1197(97.3)

791(96.1)

1988(96.8)

0.011

2

19(1.5)

28(3.4)

47(2.3)

3

10(0.8)

4(0.5)

14(0.7)

4

4(0.3)

0(0)

4(0.2)

Gravidity

1

200(21.4)

140(21.2)

340(21.3)

0.955

2鈥4

655(70.0)

460(69.7)

1115(69.9)

>=5

81(8.7)

60(9.1)

141(8.8)

Parity

0

229(24.5)

160(24.2)

389(24.4)

0.693

1

297(31.7)

226(34.2)

523(32.8)

2鈥4

394(42.1)

261(39.5)

655(41.0)

>=5

16(1.7)

13(2.0)

29(1.8)

Enrolment gestation

1st trimester

141(11.5)

87(10.6)

228(11.1)

0.439

2nd trimester

682(55.4)

426(51.8)

1108(54.0)

3rd trimester

194(15.8)

146(17.7)

340(16.6)

Term pregnancy and before labor

40(3.3)

34(4.1)

74(3.6)

Labor and delivery

82(6.7)

61(7.4)

143(7.0)

Postpartum

91(7.4)

69(8.4)

160(7.8)

Mode of delivery

Vaginal delivery

1062(86.3)

697(84.7)

1759(85.7)

0.470

Emergency CS2

127(10.3)

99(12.0)

226(11)

Elective CS

40(3.2)

25(3.0)

65(3.1)

Instrumental

1(0.1)

2(0.2)

3(0.1)

Delivery site

Study site hospital

1067(86.7)

746(90.6)

1813(88.3)

0.013

Other healthcare facility

144(11.7)

72(8.7)

216(10.5)

Home delivery

19(1.5)

5(0.6)

24(1.2)

Type of breastfeeding

Exclusive breastfeeding

1180(96.1)

791(96.5)

1971(96.2)

0.679

Exclusive formula-feeding

42(3.4)

27(3.3)

69(3.4)

Mixed-feeding

6(0.5)

2(0.2)

8(0.4)

ART initiation

Pre-conception

930(75.6)

617(75.0)

1547(75.4)

0.298

1st trimester

62(5.0)

29(3.5)

91(4.4)

2nd trimester

112(9.1)

72(8.7)

184(9.0)

3rd trimester and before labor

41(3.3)

39(4.7)

80(3.9)

Labor and delivery

55(4.5)

41(5.0)

96(4.7)

Postpartum

30(2.4)

25(3.0)

55(2.7)

  1. Foot note: 鈥1鈥 general hospital in Ethiopia setting is equivalent to secondary hospital. 鈥2鈥 means caesarean section
  2. 罢补产濒别听3 summarizes the baseline demographics, pregnancy history, and HIV-related characteristics of study participants who used either DTG- or EFV-containing ART regimens for routine PMTCT care from 2017 to 2022 in selected hospitals in Ethiopia (N鈥=鈥2053). Significant differences, highlighted in bold, correspond to a P-value of less than 0.05.