Table聽1 Clinical characteristics of participants included in the study
Characteristic | Total (n鈥�=鈥�1154) | Normal cognition (n鈥�=鈥�645) | CI (苍鈥�=鈥�509) | P value |
|---|---|---|---|---|
Age, years | 61.9鈥壜扁赌�7.8 | 60.7鈥壜扁赌�7.6 | 63.6鈥壜扁赌�7.6 | 鈥�&濒迟;鈥�0.001 |
Female, % | 529 (45.8%) | 278 (43.1%) | 251 (49.3%) | 0.035 |
Han nationality, % | 1038 (89.9%) | 584 (90.5%) | 454 (89.2%) | 0.148 |
Education, years | 11 (9, 12) | 12 (9, 12) | 9 (9, 12) | 鈥�&濒迟;鈥�0.001 |
Current smoking status, % | 357 (30.9%) | 202 (31.3%) | 155 (30.5%) | 0.752 |
Current alcohol consumption status, % | 313 (27.1%) | 183 (28.4%) | 130 (25.5%) | 0.283 |
Physical exercise, % | 819 (71.0%) | 452 (70.1%) | 367 (72.1%) | 0.452 |
Nutrition management, % | 760 (65.9%) | 451 (69.9%) | 309 (60.7%) | 0.001 |
Cardiovascular disease, % | 418 (36.2%) | 222 (34.4%) | 196 (38.5%) | 0.151 |
Cerebrovascular disease, % | 318 (27.6%) | 140 (21.7%) | 178 (35.0%) | 鈥�&濒迟;鈥�0.001 |
Hypertension, % | 773 (67.0%) | 419 (65%) | 354 (69.5%) | 0.100 |
Diabetes duration, years | 7 (1, 13) | 7 (1, 12) | 8 (2, 14) | 0.135 |
Antidiabetic agents, % | 1023 (88.6%) | 580 (89.9%) | 443 (87%) | 0.125 |
Metformin, % | 522 (45.2%) | 300 (46.5%) | 222 (43.6%) | 0.326 |
Insulin therapy, % | 537 (46.5%) | 298 (46.2%) | 239 (47.0%) | 0.799 |
Antihypertensive agents, % | 669 (58.0%) | 368 (57.1%) | 301 (59.1%) | 0.477 |
Lipid-lowering agents, % | 131 (11.4%) | 69 (10.7%) | 62 (12.2%) | 0.430 |
FPG, mmol/L | 8.08 (6.53, 10.14) | 8.09 (6.59, 10.24) | 8.08 (6.53, 10.05) | 0.482 |
TC, mmol/L | 4.81 (4.14, 5.56) | 4.85 (4.19, 5.57) | 4.79 (4.10, 5.54) | 0.256 |
TG, mmol/L | 1.56 (1.14, 2.29) | 1.62 (1.15, 2.38) | 1.51 (1.13, 2.14) | 0.056 |
HDL-c, mmol/L | 1.16 (1.01, 1.34) | 1.16 (1.02, 1.35) | 1.15 (1.00, 1.32) | 0.266 |
LDL-c, mmol/L | 3.00 (2.49, 3.52) | 3.03 (2.51, 3.57) | 2.93 (2.42, 3.47) | 0.068 |
UA, umol/L | 290.5 (242.0, 347.0) | 291.9 (237.3, 343.0) | 289.1 (246.0, 358.0) | 0.151 |
HbA1c, % | 8.5 (7.3, 10.3) | 8.5 (7.3, 10.4) | 8.5 (7.2, 10.2) | 0.677 |
SBP, mmHg | 132.90鈥壜扁赌�13.70 | 132.63鈥壜扁赌�14.20 | 133.24鈥壜扁赌�13.06 | 0.453 |
DBP, mmHg | 79.33鈥壜扁赌�8.60 | 79.31鈥壜扁赌�8.59 | 79.36鈥壜扁赌�8.63 | 0.933 |
BMI, kg/m2 | 26.17鈥壜扁赌�5.53 | 26.30鈥壜扁赌�3.63 | 26.00鈥壜扁赌�3.39 | 0.152 |
WC, cm | 91.5鈥壜扁赌�9.6 | 90.8鈥壜扁赌�9.8 | 92.3鈥壜扁赌�9.3 | 0.007 |
WHRadjBMI | 0.000鈥壜扁赌�0.0629 | -0.0127鈥壜扁赌�0.0596 | 0.0160鈥壜扁赌�0.0634 | 鈥�&濒迟;鈥�0.001 |
MoCA scores | 26 (24, 27) | 27 (26, 28) | 24 (22, 25) | 鈥�&濒迟;鈥�0.001 |