Table 2 Quality assessment of trials of the evidence for prevention in malaria in pregnancy (IPTp and ITNs) used during first or second pregnancy for preventing stillbirths
Quality assessment | Summary findings | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 听 | 听 | 听 | 听 | Directness | Intervention | Control | 听 | |||
No of studies | Design | Limitations | Consistency of results | Generalizability to population of interest | Generalizability to intervention of interest | Number of events | Denominator | Number of events | Denominator | RR (95% CI) |
IPTp for preventing stillbirths: High outcome-specific quality | ||||||||||
3 | RCT | 听 | Consistent X2 for heterogeneity (2 df) = 0.23 | High | High | 44 | 1,489 | 36 | 1,083 | 0.96 (0.62-1.50) |
ITNs for preventing stillbirths: High outcome-specific quality | ||||||||||
4 | CRCT | Not blinded | Consistent X2 for heterogeneity (3 df) = 0.03 | High | High | Unknown | Unknown | Unknown | Unknown | 0.67 (0.47-0.97) |
Effect of IPTp and ITNs combined on stillbirths : Moderate outcome-specific quality | ||||||||||
7 | RCT/ CRCT | 听 | Consistent X2 for heterogeneity (6 df) = 1.76 | High | High | Unknown | Unknown | Unknown | Unknown | 0.78 (0.59-1.03) |