Table 5 Summary of community-based studies for case management with oral antibiotics for and effect on cause specific neonatal mortality due to pneumonia
From: Effect of case management on neonatal mortality due to sepsis and pneumonia
Ref and year | Country | Setting | Study design | Therapy given | Other interventions in package | Coverage of antibiotic case management (% of those who need it) | Intervention group (N/D) | Control group (N/D) | Effect size RR (95 % CI) | |
|---|---|---|---|---|---|---|---|---|---|---|
| 听 | 听 | 听 | 听 | 听 | 听 | 听 | 听 | 听 | RR of Sepsis specific NMR | RR of Pneumonia specific NMR |
Pandey 1991[16] | Nepal | Rural | Non randomized -concurrent control | Cotrimoxazole 4 mg/kg BD for 5 days. Chloramphenicol if no improvement | Maternal education, and 15% measles immunization coverage of children | <40-70% (estimates as per study PIs) | 81/681 | 16/681 | 0.85 (0.65-1.12) | 0.89 (0.46-1.72) |
Mtango 1986[15] | Tanzania | Rural | Non randomized -concurrent control | Cotrimoxazole PO | Health education to mothers about symptoms & signs of ARI and referring severe cases to the next higher level of care. | <40-70% (estimates as per study PIs) | 37/1638 | 7/1638 | 0.70 (0.47-1.07) | 0.44 (0.18-1.07) |
Khan 1990[14] | Pakistan | Rural | Non randomized -concurrent control | CotrimoxazolePO | Qualified nurses monitored and supervised CHW activities and with assistance of the CHWs, conducted frequent, informal, interactive health education programs | <40-70% (estimates as per study PIs) | 26/2690 | 9/686 | 0.74 (0.35 - 1.57) | Did not report pneumonia specific mortality |
Bang 1990[10] | India | Rural | Non randomized -concurrent control | Cotrimoxazole 2.5 ml twice daily for 7 days | Mass health education about childhood pneumonia | 76% (for children <5) | 104/1533 | 31/1533 | 0.70 (0.54-0.91) | 0.52 (0.33-0.82) |